On 19-20 November 2021, the 42nd Informative Two-Day Pediatric Conference was held in Thessaloniki, along with the 3rd Nursers’ Day of the First Pediatric Hospital of AUTH, the Ippokrateio General Hospital as well as the Pediatric Society of Northern Greece. The two-day event was organized by CONVIN, and it took place in a hybrid mode, i.e. either online or by physical presence of those who had a vaccination or disease certificate, at Thessaloniki Concert Hall.